B.Sc University of São Paulo São paulo, Sao Paulo, Brazil
Introduction: Nanoemulsions (NEs) are clinically interesting due to their stability, biocompatibility, and reproducibility. They can be functionalized with bioactive molecules to enable therapeutic delivery through multiple administration routes (3). This study aims to develop and characterize an NE for future functionalization with antibodies against a key adhesin of the pathogenic fungus, Candidozyma auris, intended for incorporation into a hydrogel for topical skin application to impair fungal adhesion.
Learning Objectives:
Understand the rationale behind the selection and design of an NE for clinical applications.
Explain how NE composition influence stability and suitability for antibody functionalization.
Evaluate the potential of the developed nanoemulsion as a platform for future targeted therapy against C. auris.
