Creating customized 3D printing dressings with potential to deliver active compounds into the wound site

Victor Martin – Professor, 3 BoneLab, Faculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal.; 4 LAQV/REQUIMTE, University of Porto, Praça Coronel Pacheco, 4050-453 Porto, Portugal., Porto, Portugal.; Catarina Leal – Professor, 5 Departamento de Física, Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, 1959-007 Lisboa, Portugal, Lisbon, Portugal.; 6 CENIMAT/I3N, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal, Lisbon, Portugal.; 7 Centro de Física e Engenharia de Materiais Avançados, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal, Lisbon, Portugal.; Pedro Gomes – Professor, 3 BoneLab, Faculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal.; 4 LAQV/REQUIMTE, University of Porto, Praça Coronel Pacheco, 4050-453 Porto, Portugal., Porto, Portugal.; Nuno Monge – Professor, 8 Lisbon School of Education, Polytechnic University of Lisbon, Campus de Benfica do IPL, Lisbon 1549-003, Portugal.; Ana Bettencourt – Professor, 1 Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto, 1649-003 Lisboa, Portugal, Lisbon, Portugal.; 2 Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto, 1649-003 Lisboa, Portugal, Lisbon, Portugal.; Isabel Ribeiro – Professor, 1 Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto, 1649-003 Lisboa, Portugal, Lisbon, Portugal.; 2 Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto, 1649-003 Lisboa, Portugal, Lisbon, Portugal.

Introduction:

When the healing process of a wound is disrupted, chronic wounds may develop, affecting millions of patients worldwide each year (1). To overcome this issue, three-dimensional (3D) printing technology can be explored to produce 3D dressings, presenting the advantage of creating unique and customized systems tailored to the specific needs of each patient (2). Thus, our study focuses on the development of regenerative porous 3D printing dressing aiming to deliver active compounds with healing properties, such as octenidine (OCT).