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Nanomedicine and Nanoscale Delivery (Focus Group – NND)

Microfluidics - Preparation of polymer nanoparticles with an new oscillating device (FDmiX)

Karsten Mäder – Professor, Martin-Luther-University Halle-Wittenberg

    Poster Presenter(s)

  • El'za Galieva

    PhD student
    Martin-Luther-University Halle-Wittenberg
    Halle (Saale), Sachsen-Anhalt, Germany

Introduction:

FDmiX is a new, patented technology from FDX Fluid Dynamix GmbH [1]. The special geometry of the microchannels leads to a mixing of two liquids through oscillation. It is an alternative to conventional microfluidic glass chips and batch methods for the preparation of Drug Delivery Systems. To compare the new technology with conventional batch methods, polymer nanoparticles have been produced. The influence of the total flow rate (TFR) and flow rate ratio (FRR) on the particle size and particle size distribution was investigated.

Learning Objectives:

  • FDmiX is a new oscillating mixing technology.
  • FDmiX is a reproducible and robust method for preparing nanoparticles.
  • FDmiX is user-friendly.