Master's student Unicamp JUNDIAÍ, Sao Paulo, Brazil
Introduction: Oral mucositis is a severe side effect of cancer treatment with limited therapeutic options. This project develops mucoadhesive films to provide prolonged, targeted action at the lesion site. Using a matrix of sodium alginate, a biocompatible, adhesive natural polysaccharide, and glycerin, a plasticizer for mechanical optimization, these films dissolve in the oral cavity to ensure better permanence on the mucosa. This technology offers an easy-to-apply alternative to improve treatment efficacy compared to conventional delivery systems.
Learning Objectives:
To develop and characterize sodium alginate films from an experimental design for oral release.