Acting Dean Applied Science Private University Amman, 'Amman, Jordan
Introduction: Colorectal cancer (CRC) remains a leading cause of cancer mortality, requiring more effective treatment options. Dapagliflozin (DAPA), a type 2 diabetes drug, has emerging anticancer potential but suffers from low solubility and poor bioavailability. We developed a novel sedimented nanogel delivery system to enhance DAPA’s therapeutic impact in CRC.
Learning Objectives:
Describe nanoparticle-based strategies to repurpose poorly soluble drugs for oncology.
Evaluate the pharmacokinetic and pharmacodynamic improvements offered by sedimented nanogels.
Understand the anti-inflammatory and anticancer role of Dapagliflozin in colorectal cancer.
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