Resveratrol-Loaded Hyperfine Nanocapsules: Enhanced Skin Penetration and Efficacy for Advanced Cosmetics
Hyunkyung Kim – Associate Researcher, HK KOLMAR; Jungeun Lee – Senior Researcher, HK KOLMAR; Hyungjin Bae – Chief Researcher, HK KOLMAR; Jinmo Kim – Managing Director, HK KOLMAR
Research Scientist Kolmar Korea SEOUL, Republic of Korea
Introduction: Resveratrol is a natural polyphenol derived from various plants and is well known for its antioxidant activity in skin health. From a dermatological perspective, resveratrol exhibits antioxidant and anti-wrinkle effects on the skin. However, its practical application is limited by poor solubility and high sensitivity to light and heat, which reduce skin penetration and sustained bioactivity, resulting in low bioavailability. Therefore, advanced delivery systems that enhance the stability and skin penetration of resveratrol are required for skin-targeted applications.
Learning Objectives:
Understand the fabrication process of resveratrol-loaded hyperfine nanocapsules for enhanced skin delivery
Explain the advantages of RVT@HNCs in improving resveratrol's stability, skin penetration, and bioavailability
Evaluate the biological efficacy of RVT@HNCs compared to free resveratrol in vitro assay
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