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Nanomedicine and Nanoscale Delivery (Focus Group – NND)

Pre-Formulation of Amphiphilic Cyclodextrin Nanosystems

Cátia Domingues – PhD, Faculty of Pharmacy of the University of Coimbra; Ana Figueiras – PhD, Faculty of Pharmacy of the University of Coimbra; Ivana Jarak – PhD, Faculty of Pharmacy of the University of Coimbra
Introduction:

Cyclodextrins (CDs) have sparked widespread interest as drug delivery systems due to their unique molecular structure, attractive properties, and remarkable versatility. Beyond their traditional role as host molecules, CDs can be chemically modified into amphiphilic derivatives that can self-assemble into different types of nanocarriers. These amphiphilic CDs are specifically designed to overcome the limitations of natural CDs, thus expanding their therapeutic applications [1].

Learning Objectives:

  • 1. Understanding the structural features of cationic amphiphilic CDs and their self-assembly capacity.
  • 2. Evaluate the drug encapsulation capacity and efficiency of CD-based nanoparticles