Mentha genus plant extract-loaded liposomes for cosmetic and dermopharmaceutical applications
Nádia Santos – MSc Student, Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra; Ana Macário-Soares – PhD Student, Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra; Mariana Antunes – MSc, Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra; Francisco Veiga – Full Professor, Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra; Patrícia Pires – Assistant Professor, Department of Medical Sciences, University of Aveiro; Ana Paiva-Santos – Associate Professor, Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra
Assistant Professor Faculty of Pharmacy of University of Coimbra Coimbra, Portugal
Introduction: Mentha genus plant extracts have significant antioxidant, anti-inflammatory, anti-infective, and anticancer properties, with additional cosmetic effects on the skin, hence being ideal for dermopharmaceutic and cosmetic applications (1). Nanoencapsulation can enhance topical delivery, providing drug protection, and enabling controlled release. To incorporate plant extracts, liposomes are regarded as the most adequate, enabling the encapsulation of both water-soluble and fat-soluble compounds (2). The purpose of this work was to encapsulate a novel Mentha genus plant extract into liposomes.
Learning Objectives:
Describe that a never-before-encapsulated plant extract was successfully encapsulated (EE% up to 70%).
Explain the physicochemical characteristics of the developed liposomes for skin permeation and retention.
Define the potential of plant extract-loaded liposomes for dermopharmaceutical and cosmetic applications.
