Full Schedule

7:00 AM - 8:00 AM WEST

LX Factory Wake-Up Challenge (via MAAT)

Networking

7:00 AM - 8:00 AM WEST

LX Factory Wake-Up Challenge: Walking Map

Presenter:

Networking

7:30 AM - 6:00 PM WEST

Registration Hours

Room: Foyer A

Registration Hours

7:30 AM - 7:00 PM WEST

Speaker Ready Room Hours

Room: Room 104

Speaker Ready Room Hours

8:00 AM - 9:00 AM WEST

CRS Meets AIMBE: Building Trust in Science: Public Engagement and Advocacy for an International Biomedical Research Community

Room: Auditorium I

Chair and Speaker: – American Institute for Medical and Biological Engineering (AIMBE)

CRS Meet Up Session

8:00 AM - 8:10 AM WEST

Opening Remarks & Presentation by Maria Vicent and Dawn Beraud

Room: Auditorium I

Invited Speaker: – American Institute for Medical and Biological Engineering (AIMBE)

Invited Speaker: – CIPF - Centro de Investigación Príncipe Felipe

CRS Meet Up Session

8:10 AM - 8:25 AM WEST

Presentation by Mike King

Room: Auditorium I

Invited Speaker: – Rice University

CRS Meet Up Session

8:25 AM - 8:40 AM WEST

Presentation by Paolo Decuzzi

Room: Auditorium I

Invited Speaker: – Chiromesh Therapeutics | Italian Institute of Technology

CRS Meet Up Session

8:40 AM - 8:55 AM WEST

Moderated Q&A

Room: Auditorium I

CRS Meet Up Session

8:55 AM - 9:00 AM WEST

Closing Remarks & Workshop Survey

Room: Auditorium I

CRS Meet Up Session

8:00 AM - 9:00 AM WEST

YSC Mentorship Event: Mentorship in Transition

Room: Auditorium 5

Chair: – i3S- Instituto de Investigação e Inovação em Saúde, University of Porto

YSC Session

Presented By

8:00 AM - 9:00 AM WEST

Bridging disciplines in the fight against glioblastoma: my academic journey

Room: Auditorium 5

Speaker: – Institute of Neurophysiopathology - CNRS, Aix-Marseille University

YSC Session

8:00 AM - 9:00 AM WEST

Bridging the Gap: The Mentors Who Shaped My Journey

Room: Auditorium 5

Speaker: – Queen's University Belfast

YSC Session

8:00 AM - 9:00 AM WEST

Lessons from Navigating Career Changes

Room: Auditorium 5

Speaker: – Capsugel France SAS / Lonza

YSC Session

8:00 AM - 9:00 AM WEST

Navigating the job market as a researcher - thoughts by Filipe Almeida

Room: Auditorium 5

Speaker: – Nature Biomedical Engineering

YSC Session

9:00 AM - 10:00 AM WEST

Technical Forums III

Industry Session

9:00 AM - 10:00 AM WEST

Breaking the Injection Barrier Using Innovative Technologies for Oral Delivery of Midsize and Macromolecules

Room: Auditorium 6

Speaker: – Catalent Pharma Solutions

Industry Session

Sponsored By

9:00 AM - 10:00 AM WEST

Enabling Innovation in Polymer Therapeutics Through Scientific Alliance

Room: Auditorium 2

Chair and Speaker: – Tosoh Bioscience GmbH

Speaker: – CIPF - Centro de Investigación Príncipe Felipe

Speaker: – Tosoh Bioscience GmbH

Speaker: – Curapath

Industry Session

Sponsored By

9:00 AM - 10:00 AM WEST

Hyaluronic Acid Nanogel (Sonanos™): A Next-Generation Pharmaceutical Excipient for Injectable Formulations as a Sustained Release Agent and Solubilizer

Room: Auditorium 3/4

Speaker: – Asahi Kasei Corporation

Industry Session

Sponsored By

9:00 AM - 10:00 AM WEST

Learning to Deliver: Machine Learning–Guided Lipid Nanoparticles Enabled by High-Throughput Fabrication for Efficient RNA Transport Using Dionamix NanoStation Platform

Room: Auditorium 7

Speaker: – University of British Columbia

Speaker: – Dionamix Scientific inc.

Industry Session

Sponsored By

10:00 AM - 10:30 AM WEST

Morning Coffee Break | Exhibit Hall & Posters

Room: Pavilion 2

Coffee BreakExhibit HallPoster HoursBreakNetworking

10:30 AM - 12:30 PM WEST

Tech Session IV: Oral Delivery II

Room: Auditorium 2

Chair: – School of Engineering, Brown University, Providence, RI, USA

Co-Chair: – The University of Queensland

Technical Session IVOral Delivery (Focus Group - OrD)

10:30 AM - 10:53 AM WEST

Tips & Tricks for Oral Delivery of Peptides using SNEDDS

Room: Auditorium 2

Invited Speaker: – University of Copenhagen

Technical Session IVOral Delivery (Focus Group - OrD)

10:53 AM - 11:16 AM WEST

Solving the oral peptide puzzle: Formulation, barrier modulation, and alternative mucosal routes

Room: Auditorium 2

Invited Speaker: – Novo Nordisk

Technical Session IVOral Delivery (Focus Group - OrD)

11:16 AM - 11:26 AM WEST

Surface PEGylation density optimization enhances oral delivery of T7-functionalized liposomes

Room: Auditorium 2

Oral Abstract Speaker: – West China School of Pharmacy, Sichuan University

Technical Session IVOral Delivery (Focus Group - OrD)

11:26 AM - 11:36 AM WEST

Circadian Rhythm–Matched Programmable Oral Tablets via 3D-Printed Photocrosslinkable Polyanhydrides

Room: Auditorium 2

Oral Abstract Speaker: – Western University

Technical Session IVOral Delivery (Focus Group - OrD)

11:36 AM - 11:46 AM WEST

Additive Manufacturing of Ternary Lipid Matrices via FDM: The Role of Release Enhancers

Room: Auditorium 2

Oral Abstract Speaker: – Research Center Pharmaceutical Engineering

Technical Session IVOral Delivery (Focus Group - OrD)

11:46 AM - 11:56 AM WEST

Feasibility of ultrasound cavitation agent mediated gastrointestinal drug delivery

Room: Auditorium 2

Oral Abstract Speaker: – University of Oxford

Technical Session IVOral Delivery (Focus Group - OrD)

11:56 AM - 12:06 PM WEST

Metal-organic framework for oral antibody delivery for colorectal cancer treatment

Room: Auditorium 2

Oral Abstract Speaker: – Université catholique de Louvain

Technical Session IVOral Delivery (Focus Group - OrD)

12:06 PM - 12:16 PM WEST

Hitchhiking on Chylomicrons: The Role of Oleic Acid on Lymphatic Absorption of bRo5 Drugs

Room: Auditorium 2

Oral Abstract Speaker: – AbbVie Deutschland GmbH & Co. KG

Technical Session IVOral Delivery (Focus Group - OrD)

12:16 PM - 12:26 PM WEST

Spatial integration of antimicrobial peptides controls release and activity in oral delivery systems

Room: Auditorium 2

Oral Abstract Speaker: – Sao Paulo State University

Technical Session IVOral Delivery (Focus Group - OrD)

10:30 AM - 12:30 PM WEST

Tech Session IV: Immuno Delivery III

Room: Auditorium 6

Chair:

Co-Chair: – Australian Centre for NanoMedicine, University of New South Wales

Technical Session IVImmuno Delivery (Focus Group - ID)

10:30 AM - 10:53 AM WEST

Academia Invited Speaker Presentation

Room: Auditorium 6

Invited Speaker: – Georgia Institute of Technology

Technical Session IVImmuno Delivery (Focus Group - ID)

10:53 AM - 11:16 AM WEST

Advanced Functionalization Strategies for Lipid Nanoparticles using CliCr® technology

Room: Auditorium 6

Oral Abstract Speaker: – Curapath

Technical Session IVNanomedicine and Nanoscale Delivery (Focus Group - NND)

11:16 AM - 11:26 AM WEST

Multivalent Ligand Armed NK Cells for Immunological Synapse Stabilizing

Room: Auditorium 6

Oral Abstract Speaker: – SiChuan University

Technical Session IVImmuno Delivery (Focus Group - ID)Bioengineering (Focus Group - BE)

11:26 AM - 11:36 AM WEST

In vivo Degradable Nanocarriers for Immunodrug Delivery and Gene Interference

Room: Auditorium 6

Oral Abstract Speaker: – Center of Polymers for Life, Julius-Maximilians-Universität Würzburg

Technical Session IVImmuno Delivery (Focus Group - ID)

11:36 AM - 11:46 AM WEST

Efficacy of allergen-loaded nanoparticles for allergen specific immunotherapy

Room: Auditorium 6

Oral Abstract Speaker: – IBIMA Plataforma BIONAND

Technical Session IVNanomedicine and Nanoscale Delivery (Focus Group - NND)

11:46 AM - 11:56 AM WEST

Bispecific DC-CD4 Nanovesicles Enable Efficient Lymph Node Programming of Antigen Specific Immune Tolerance

Room: Auditorium 6

Oral Abstract Speaker: – Soochow University

Technical Session IVImmuno Delivery (Focus Group - ID)

11:56 AM - 12:06 PM WEST

Macrophage-targeted nanotherapy enables immune reprogramming in inflammatory bowel disease

Room: Auditorium 6

Oral Abstract Speaker: – National Tsing Hua University/ Academia Sinica

Technical Session IVImmuno Delivery (Focus Group - ID)

12:06 PM - 12:16 PM WEST

Engineered Saccharomyces boulardii for Local Immunotherapy Delivery Ameliorates Colitis

Room: Auditorium 6

Oral Abstract Speaker: – University of North Carolina at Chapel Hill

Technical Session IVImmuno Delivery (Focus Group - ID)

10:30 AM - 12:30 PM WEST

Tech Session IV: Manufacturing and Process Scale-Up II

Room: Auditorium 3/4

Chair: – Department of Pharmaceutics - Ghent University - Belgium

Co-Chair: – Glatt Pharmaceutical Services GmbH & Co. KG

Technical Session IVManufacturing and Process Scale-Up

10:30 AM - 10:53 AM WEST

Industrial Development of mRNA Lipid Nanoparticles: Linking Structure, Performance, and Manufacturability

Room: Auditorium 3/4

Invited Speaker: – AstraZeneca

Technical Session IVManufacturing and Process Scale-Up

10:53 AM - 11:16 AM WEST

Pharmacokinetic clinical trial of 3D-printed pimobendan tablets in Beagle dogs

Room: Auditorium 3/4

Local Chapter Speaker: – Federal University of Rio Grande do Sul

Technical Session IVManufacturing and Process Scale-Up

11:16 AM - 11:26 AM WEST

High-Throughput Aerofoiled-Based Microfluidics for Screening and AI-Driven Optimization of Lipid Nanoparticles

Room: Auditorium 3/4

Oral Abstract Speaker: – University College Dublin

Technical Session IVManufacturing and Process Scale-Up

11:26 AM - 11:36 AM WEST

Modular Continuous Reactor Platform for Scalable Manufacturing of Taste-Masked Clarithromycin Nanoparticles

Room: Auditorium 3/4

Oral Abstract Speaker: – The Hashemite University \ Faculty of Pharmaceutical sciences

Technical Session IVManufacturing and Process Scale-Up

11:36 AM - 11:46 AM WEST

Programming Shape and Therapy: 4D- Scaffolds for Minimally Invasive Drug Delivery

Room: Auditorium 3/4

Oral Abstract Speaker: – University of Pavia

Technical Session IVManufacturing and Process Scale-Up

11:46 AM - 11:56 AM WEST

Impact of Particle Agglomeration & Depot Microstructure on In Vivo Performance of Long Acting Injectable Suspension

Room: Auditorium 3/4

Oral Abstract Speaker: – University of Connecticut

Technical Session IVManufacturing and Process Scale-Up

11:56 AM - 12:06 PM WEST

Scalable LNP Manufacturing: TFR-Independent Quality, Mixer Effects and Process Intensification

Room: Auditorium 3/4

Oral Abstract Speaker: – leon-nanodrugs GmbH

Technical Session IVManufacturing and Process Scale-Up

12:06 PM - 12:16 PM WEST

Print, disperse, deliver: personalized water-soluble 3D-printed medicines for oral drug delivery

Room: Auditorium 3/4

Oral Abstract Speaker: – Universidade Federal do Rio Grande do Sul

Technical Session IVManufacturing and Process Scale-Up

10:30 AM - 12:30 PM WEST

Tech Session IV: Delivery to the Nervous System II

Room: Auditorium 8

Chair: – School of Pharmacy, Sungkyunkwan University

Co-Chair: – DSTL

Technical Session IVDelivery to the Nervous System

10:30 AM - 10:53 AM WEST

Nano delivery approaches to modulate cellular redox state in response to neonatal brain injury

Room: Auditorium 8

Invited Speaker: – University of Washington

Technical Session IVDelivery to the Nervous System

10:53 AM - 11:16 AM WEST

Industry Invited Speaker Presentation

Room: Auditorium 8

Invited Speaker: – Lilly

Technical Session IVDelivery to the Nervous System

11:16 AM - 11:26 AM WEST

An Automated and Barcoded Platform for Scalable In Vivo Screening of Brain-Targeted Lipid Nanoparticles

Room: Auditorium 8

Oral Abstract Speaker: – Univeristy of Texas at Dallas

Technical Session IVNanomedicine and Nanoscale Delivery (Focus Group - NND)

11:26 AM - 11:36 AM WEST

Triple Cargo Strategy: VCAM-Targeted LNPs for Neurological Disorders

Room: Auditorium 8

Oral Abstract Speaker: – Temple University

Technical Session IVDelivery to the Nervous System

11:36 AM - 11:46 AM WEST

Formulation of fluorinated polyester sonosensitive agents for ultrasound brain therapy and imaging

Room: Auditorium 8

Oral Abstract Speaker: – CNRS

Technical Session IVDelivery to the Nervous System

11:46 AM - 11:56 AM WEST

Enhanced Malignant Brain Tumor Targeting via Size-Tunable Polymeric Nanoruler

Room: Auditorium 8

Oral Abstract Speaker: – The University of Tokyo

Technical Session IVDelivery to the Nervous System

11:56 AM - 12:06 PM WEST

An in vitro platform to test therapeutic ultrasound in nerve injury

Room: Auditorium 8

Local Chapter Speaker: – University of Auckland

Technical Session IVDelivery to the Nervous System

12:06 PM - 12:16 PM WEST

Machine-learning-guided and Ultrasound-responsive Nanotherapeutic Platform for Chronic Pain Management

Room: Auditorium 8

Oral Abstract Speaker: – University of Texas at Austin

Technical Session IVDelivery to the Nervous System

12:16 PM - 12:26 PM WEST

Tri-Targeted Nanoparticles for Blood–Brain Barrier Crossing and T Cell–Mediated Immunotherapy in Glioblastoma

Room: Auditorium 8

Oral Abstract Speaker: – Gulbenkian Institute for Molecular Medicine

Technical Session IVDelivery to the Nervous System

10:30 AM - 12:30 PM WEST

Tech Session IV: Skin & Mucosal Delivery III

Room: Auditorium 7

Chair: – Georgia Institute of Technology

Co-Chair: – RWTH Aachen University Hospital

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

10:30 AM - 10:53 AM WEST

Dermocosmetics Delivery Science: from formulation to clinical evidence

Room: Auditorium 7

Invited Speaker: – Curtin Univeristy

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

10:53 AM - 11:16 AM WEST

Temporal Progression of Inflammation and Healing in Porcine Tissue after Injection of Long-Acting Formulations

Room: Auditorium 7

Oral Abstract Speaker: – Gilead Sciences

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

11:16 AM - 11:26 AM WEST

Next-Generation Microneedles with Novel Visual Indicators for Precision Peptide Delivery

Room: Auditorium 7

Oral Abstract Speaker: – Queen's University Belfast

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

11:26 AM - 11:36 AM WEST

Overcoming Resistance in Local Refractory Melanoma via Dual-Targeted Lipid Nanoparticles

Room: Auditorium 7

Oral Abstract Speaker: – Institute for Research and Innovation in Health (I3S), University of Porto

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

11:36 AM - 11:46 AM WEST

Tunable extracellular matrix hydrogels containing Helminth egg antigen for accelerated diabetic wound healing

Room: Auditorium 7

Oral Abstract Speaker: – Yale University

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

11:46 AM - 11:56 AM WEST

Unravelling the Impact of Nanoparticle Surface Features on Microfold Cell Interactions

Room: Auditorium 7

Oral Abstract Speaker: – Monash Institute of Pharmaceutical Science

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

11:56 AM - 12:06 PM WEST

Achieving oromucosal absorption of a GLP-1 peptide analogue: proof of principle for sub-lingual films in pigs

Room: Auditorium 7

Oral Abstract Speaker: – UNIVERSITY COLLEGE DUBLIN

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

12:06 PM - 12:16 PM WEST

Clinical trial of marking dogs and cats with microneedle patch tattoos to indicate sterilization status

Room: Auditorium 7

Oral Abstract Speaker: – Georgia Tech

Technical Session IVSkin and Mucosal Delivery (Focus Group - SMD)

10:30 AM - 12:30 PM WEST

Tech Session IV: Gene Delivery & Gene Editing II: CRS Meets ESGCT

Room: Auditorium I

Chair: – University Medical Center Groningen

Co-Chair: – University Medical Center Groningen

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

10:30 AM - 10:53 AM WEST

ExpEditing AAV gene therapy

Room: Auditorium I

Invited Speaker: – Telethon Institute of Genetics and Medicine (TIGEM)

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

10:53 AM - 11:16 AM WEST

PeptiCRAd: From Lab Discovery to the ClinicA Highly Customizable Platform for Personalized Cancer Vaccines

Room: Auditorium I

Invited Speaker: – University of Helsinki

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

11:16 AM - 11:26 AM WEST

Triazine lipids as a platform for mRNA delivery

Room: Auditorium I

Oral Abstract Speaker: – University of Kentucky

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

11:26 AM - 11:36 AM WEST

Hybrid nanoassemblies combine active and endogenous targeting to enable siRNA delivery for lung cancer treatment

Room: Auditorium I

Oral Abstract Speaker: – University of Santiago de Compostela

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

11:36 AM - 11:46 AM WEST

Hydrophobic Tuning of Lipo-Xenopeptides Modulated Endosomal Escape and Enhanced mRNA Transfection Efficiency

Room: Auditorium I

Oral Abstract Speaker: – Ludwig-Maximilians-University Munich

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

11:46 AM - 11:56 AM WEST

Immunogenic silica nanoparticles and silicified cells for ovarian cancer

Room: Auditorium I

Oral Abstract Speaker: – University of New Mexico

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

11:56 AM - 12:06 PM WEST

Advanced Formulations Potentiate AAV Vectors for Cancer Gene Therapy

Room: Auditorium I

Local Chapter Speaker: – Sichuan University

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

12:06 PM - 12:16 PM WEST

Systemic Heart-Selective Lipid Nanoparticles for High-Efficiency In Vivo Delivery and Cardiomyocyte Gene Editing

Room: Auditorium I

Oral Abstract Speaker: – METiS TechBio

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

12:16 PM - 12:26 PM WEST

Investigating type of ionizable lipids in mRNA lipid nanoparticle vaccines to induce respiratory mucosal immunity

Room: Auditorium I

Oral Abstract Speaker: – Vaccines and Infectious Disease Organization (VIDO), University of Saskatchewan

Technical Session IVGene Delivery and Gene Editing (Focus Group - GDGE)

12:30 PM - 1:30 PM WEST

Plenary Lecture III: Electrostatic Nano-Assemblies for Biomedicine

Room: Auditorium I

Chair: – i3S . Instituto de Investigação e Inovação em Saúde, University of Porto

Plenary Speaker: – Koch Institute for Integrative Cancer Research | Massachusetts Institute of Technology

Plenary Session

1:30 PM - 2:30 PM WEST

ADDR Board Meeting

Room: Room 105

Journal Session

1:30 PM - 2:30 PM WEST

C&DP Board Meeting

Room: Room 106

Committee Meeting

1:30 PM - 2:30 PM WEST

DDTR Editorial Board Meeting

Room: Room 107

Committee MeetingJournal Session

1:30 PM - 2:30 PM WEST

Focus Group (FG) Leadership Committee Meeting

Room: Auditorium 2

FG SessionCommittee Meeting

1:30 PM - 2:30 PM WEST

IAG Meeting

Room: Room 108

Industry SessionCommittee Meeting

1:30 PM - 2:30 PM WEST

International Chapters Meeting

Room: Auditorium 3/4

Committee Meeting

1:30 PM - 2:30 PM WEST

Lunch Break | Exhibit Hall & Posters

Room: Pavilion 2

Lunch BreakFood & Beverage ProvidedExhibit HallPoster HoursBreakNetworking

1:30 PM - 2:30 PM WEST

Mix-It-Up Lunch – Access in Science

Room: Auditorium 6

Chair: – Gyan Ganga Institute of Technology and Sciences

Co-Chair: – Tufts University

Co-Chair: – Rice University

GMEC Session

Presented By

1:30 PM - 2:30 PM WEST

YSC Meet & Greet with a Luminary

Room: Auditorium 5

Chair: – i3S- Instituto de Investigação e Inovação em Saúde, University of Porto

YSC Session

Presented By

1:30 PM - 1:35 PM WEST

CRS Exceptional Leadership Award Presentation

Room: Auditorium 5

Award Winner: – University of Valencia

YSC Session

2:30 PM - 4:30 PM WEST

Tech Session V: Nanomedicine & Nanoscale Delivery IV

Room: Auditorium 2

Chair:

Co-Chair: – Universidade Federal de Goias

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:30 PM - 2:53 PM WEST

Academia Invited Speaker Presentation

Room: Auditorium 2

Invited Speaker: – PENN

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:53 PM - 3:16 PM WEST

AI and Automation for Smarter Oral Nanomedicine Development

Room: Auditorium 2

Invited Speaker: – Intrepid Labs

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:16 PM - 3:26 PM WEST

A bioorthogonal luminescent approach for intracellular delivery quantitative analysis

Room: Auditorium 2

Oral Abstract Speaker: – University of Helsinki

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:26 PM - 3:36 PM WEST

Efficient Nanoneedle transfection requires Caveolar Endocytosis

Room: Auditorium 2

Oral Abstract Speaker: – King's College London

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:36 PM - 3:46 PM WEST

Targeted Mitochondria Sequestration and Degradation via Modular Nanoassemblies Mimicking p62 Aggregates

Room: Auditorium 2

Oral Abstract Speaker: – Sichuan University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:46 PM - 3:56 PM WEST

Biomimetic Nanoparticles Co-delivering Gemcitabine and IKKβ Inhibitor Reverse PDAC Stemness

Room: Auditorium 2

Oral Abstract Speaker: – University of Nebraska Medical Center

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:56 PM - 4:06 PM WEST

Design of Magnetically Actuated Biodegradable Fibre-based Scaffolds for Remote Modulation of Drug Release

Room: Auditorium 2

Oral Abstract Speaker: – Helmut Schmidt University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

4:06 PM - 4:16 PM WEST

Calcium phosphate nanoparticles enable efficient delivery of therapeutic siRNA for cardiac gene silencing

Room: Auditorium 2

Oral Abstract Speaker: – ISSMC-CNR and University of Parma, Italy

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:30 PM - 4:30 PM WEST

Tech Session V: Advanced Therapies

Room: Auditorium 3/4

Chair: – Bluepharma

Co-Chair: – Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL)

Technical Session VAdvanced Therapies

Sponsored By

2:30 PM - 2:32 PM WEST

Bluepharma Intro Presentation

Room: Auditorium 3/4

Invited Speaker: – Bluepharma

Technical Session VAdvanced Therapies

Sponsored By

2:32 PM - 2:55 PM WEST

Designing Scalable RNA-Lipid Nanoparticles Through a QbD Approach

Room: Auditorium 3/4

Invited Speaker: – Bluepharma

Technical Session VAdvanced Therapies

2:55 PM - 3:18 PM WEST

From Tumor Targeting to Immune Activation: Engineering Immunomodulatory LNPs for Cancer Immunotherapy

Room: Auditorium 3/4

Invited Speaker: – University of Coimbra

Technical Session VAdvanced Therapies

3:18 PM - 3:28 PM WEST

Precision mRNA therapy for pre-eclampsia: a mechanism-driven approach for LNP delivery to the placenta

Room: Auditorium 3/4

Oral Abstract Speaker: – Rice University

Technical Session VAdvanced Therapies

3:28 PM - 3:38 PM WEST

Engineering lipid self-assembling nanoparticles for Safe and Efficient CRISPR/CAS9-Based Editing

Room: Auditorium 3/4

Oral Abstract Speaker: – Università degli Studi di Napoli, Federico II

Technical Session VAdvanced Therapies

3:38 PM - 3:48 PM WEST

The Clearance of Human Cytomegalovirus Using CRISPR/Cas9 RNA Lipid Nanoparticles

Room: Auditorium 3/4

Oral Abstract Speaker: – University of Toronto

Technical Session VAdvanced Therapies

3:48 PM - 3:58 PM WEST

Lipid nanoparticles mediated CRISPR/Cas9 co-targeting for the treatment of Amyotrophic Lateral Sclerosis

Room: Auditorium 3/4

Oral Abstract Speaker: – University of Hong Kong

Technical Session VAdvanced Therapies

3:58 PM - 4:08 PM WEST

Noble linear mRNA structures for prolonged protein expression

Room: Auditorium 3/4

Local Chapter Speaker: – Ewha Womans University

Technical Session VAdvanced Therapies

4:08 PM - 4:18 PM WEST

Optimizing liposomal doxorubicin efficacy: Pharmacological tumor priming to overcome delivery barriers

Room: Auditorium 3/4

Oral Abstract Speaker: – Mashhad university of Medical Sciences

Technical Session VAdvanced Therapies

2:30 PM - 4:30 PM WEST

Tech Session V: Skin & Mucosal Delivery IV

Room: Auditorium 6

Chair: – Boehringer Ingelheim

Co-Chair: – Université de Montréal

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

2:30 PM - 2:53 PM WEST

Milk-derived Exosomes as a Natural Platform for Oral Gene Therapy

Room: Auditorium 6

Invited Speaker: – Korea Institute of Science and Technology

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

2:53 PM - 3:16 PM WEST

Addressing Nasal Delivery Challenges: Integrated Formulation and Device Strategies for Predictive Performance

Room: Auditorium 6

Invited Speaker: – Hovione

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

3:16 PM - 3:26 PM WEST

Surface-engineered Muco-penetrating Nanocrystals for Nose-to-Brain Therapy in Cerebral Malaria

Room: Auditorium 6

Oral Abstract Speaker: – Queen's University Belfast

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)Delivery to the Nervous System

3:26 PM - 3:36 PM WEST

Antibacterial inhalable chitosan nanoparticles for resistant lung infections: Impact of structural organization

Room: Auditorium 6

Oral Abstract Speaker: – University of Campania "Luigi Vanvitelli"

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

3:36 PM - 3:46 PM WEST

Next‑generation nasal vaccines: engineering mRNA-nanoassemblies for in vivo mucosal delivery

Room: Auditorium 6

Oral Abstract Speaker: – CiMUS - University of Santiago de Compostela

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

3:46 PM - 3:56 PM WEST

Engineered hybrid nanoparticles efficiently overcome mucus and aerosol barriers for respiratory mRNA delivery

Room: Auditorium 6

Oral Abstract Speaker: – CNRS LBTI

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

3:56 PM - 4:06 PM WEST

Spray-delivered gellan–chitosan hydrogels enabling dual nanotherapeutic delivery for infected and damaged skin

Room: Auditorium 6

Oral Abstract Speaker: – University G. d’Annunzio of Chieti e Pescara

Technical Session VSkin and Mucosal Delivery (Focus Group - SMD)

2:30 PM - 4:30 PM WEST

Tech Session V: Nanomedicine & Nanoscale Delivery V

Room: Auditorium 7

Chair: – Novo Nordisk

Co-Chair: – University of Lisbon

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

Sponsored By

2:30 PM - 2:40 PM WEST

Novo Nordisk Sponsor Intro

Room: Auditorium 7

Invited Speaker: – Novo Nordisk

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

Sponsored By

2:40 PM - 3:03 PM WEST

Academia Invited Speaker Presentation

Room: Auditorium 7

Invited Speaker: – Tel Aviv University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:03 PM - 3:26 PM WEST

Designing and translating bioengineering innovations for advanced therapeutic delivery

Room: Auditorium 7

Invited Speaker: – SPARTA Biodiscovery

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:26 PM - 3:36 PM WEST

Breaking the Neural Mitochondria-Neutrophil Loop with a Targeted Drug Delivery Platform for Spinal Cord Injury

Room: Auditorium 7

Oral Abstract Speaker: – Sichuan University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:36 PM - 3:46 PM WEST

APC-Targeted Nanovaccine Enhances Immunity and Boosts Efficacy of Standard and KRAS-Targeted Therapies in PDAC

Room: Auditorium 7

Oral Abstract Speaker: – Tel-Aviv university

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:46 PM - 3:56 PM WEST

Immunoglobulin M as a Tumor Targeting Tissue Biomarker for Cancer Nanomedicine Accumulation and Extravasation

Room: Auditorium 7

Oral Abstract Speaker: – Uniklinik RWTH Aachen

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)Imaging in Drug Delivery

3:56 PM - 4:06 PM WEST

Modular PLGA nanoparticles for activatable and targeted tumour imaging by 19F MRI

Room: Auditorium 7

Oral Abstract Speaker: – Wageningen University and Research

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)Imaging in Drug Delivery

4:06 PM - 4:16 PM WEST

Flame Synthesis of Fractal-Like Nanoaggregates for Deep-Tissue Bioimaging

Room: Auditorium 7

Oral Abstract Speaker: – Science for Life Laboratory, Stockholm University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)Imaging in Drug Delivery

4:16 PM - 4:26 PM WEST

Microbubble Shell Engineering Enhances Ultrasound-Mediated Drug Delivery

Room: Auditorium 7

Oral Abstract Speaker: – RWTH Aachen University Hospital

Technical Session IINanomedicine and Nanoscale Delivery (Focus Group - NND)Imaging in Drug Delivery

2:30 PM - 4:30 PM WEST

Tech Session V: Nanomedicine & Nanoscale Delivery VI

Room: Auditorium 8

Chair: – Eindhoven University of Technology

Co-Chair: – Technion- Israel Institute of Technology

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:30 PM - 2:53 PM WEST

mRNA Delivery to the Retina restores REP1 Function in an Inherited Retinal Degenerative Disease

Room: Auditorium 8

Invited Speaker: – Fundação Champalimaud

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:53 PM - 3:16 PM WEST

A Next-Generation Modular Ionizable Lipid Nanoparticle Platform for Gene and Cell Therapy Applications

Room: Auditorium 8

Oral Abstract Speaker: – Certest Biotec S.L.

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)Gene Delivery and Gene Editing (Focus Group - GDGE)

3:16 PM - 3:26 PM WEST

Innovative phage therapy for chronic osteomyelitis: controlled intrabone release of GMP therapeutic phages

Room: Auditorium 8

Oral Abstract Speaker: – Hospices Civils de Lyon

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:26 PM - 3:36 PM WEST

GD2Fab-directed Ionizable Lipid Nanoparticles for Precision siRNA Therapy in Neuroblastoma

Room: Auditorium 8

Oral Abstract Speaker: – Southeast University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)Gene Delivery and Gene Editing (Focus Group - GDGE)

3:36 PM - 3:46 PM WEST

Lipid Nanoparticle-Mediated Spatiotemporal Modulation of NF-kB Activation to Treat Atherosclerosis

Room: Auditorium 8

Oral Abstract Speaker: – University of Chicago

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:46 PM - 3:56 PM WEST

Flame-made nanocarriers of antimicrobial biomolecules against antibiotic resistant bacteria in skin wounds

Room: Auditorium 8

Oral Abstract Speaker: – SciLifeLab, Stockholm University

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

3:56 PM - 4:06 PM WEST

Enhancing KRAS mRNA-LNP Vaccine Efficacy through Tumor Microenvironment Normalization in Desmoplastic Tumors

Room: Auditorium 8

Oral Abstract Speaker: – University of Cyprus

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

4:06 PM - 4:16 PM WEST

Extracellular vesicle mimetics for the targeted treatment of metastatic brain cancer

Room: Auditorium 8

Oral Abstract Speaker: – University of Groningen

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

4:16 PM - 4:26 PM WEST

Formulation Strategies for Pulmonary Delivery of GMP-Bacteriophages

Room: Auditorium 8

Oral Abstract Speaker: – Edouard Herriot Hospital

Technical Session VNanomedicine and Nanoscale Delivery (Focus Group - NND)

2:30 PM - 4:30 PM WEST

Tech Session V: Bioengineering III: CRS Meets TERMIS

Room: Auditorium I

Chair: – University Medical Center Groningen

Co-Chair:

Technical Session VBioengineering (Focus Group - BE)

2:30 PM - 2:53 PM WEST

Academia Invited Speaker Presentation

Room: Auditorium I

Invited Speaker: – University of Porto

Technical Session VBioengineering (Focus Group - BE)

2:53 PM - 3:16 PM WEST

Engineering biomaterials to control cellular (micro)environment

Room: Auditorium I

Invited Speaker: – Eindhoven University of Technology

Technical Session VBioengineering (Focus Group - BE)

3:16 PM - 3:26 PM WEST

MOMONA-seq: in vivo multi-omic single-cell LNP screen for mRNA vaccine and cancer immunotherapy discovery

Room: Auditorium I

Oral Abstract Speaker: – University of British Columbia, Vancouver

Technical Session VBioengineering (Focus Group - BE)Immunodelivery (Focus Group - ID)

3:26 PM - 3:36 PM WEST

Functionalized miR-loaded lipid-nanocapsules for regeneration of intervertebral disc to treat low back pain

Room: Auditorium I

Oral Abstract Speaker: – RMeS lab INSERM UMR1229, university of Nantes.

Technical Session VBioengineering (Focus Group - BE)Nanomedicine and Nanoscale Delivery (Focus Group - NND)

3:36 PM - 3:46 PM WEST

Protein-Producing Lipid Particles Synthesize Exenatide Enhancing Insulin Secretion in Human Pancreatic Islets

Room: Auditorium I

Oral Abstract Speaker: – i3S – Instituto de Investigação e Inovação em Saúde

Technical Session VBioengineering (Focus Group - BE)

3:46 PM - 3:56 PM WEST

Disease-severity-responsive nanoparticles enable precise RNA therapy for osteoarthritis

Room: Auditorium I

Oral Abstract Speaker: – Brigham and Women's Hospital, Harvard Medical School

Technical Session VBioengineering (Focus Group - BE)Gene Delivery and Gene Editing (Focus Group - GDGE)

3:56 PM - 4:06 PM WEST

MMP13-responsive siRNA delivery system for self-regulated control of hypertrophy in MSC-based cartilage repair

Room: Auditorium I

Oral Abstract Speaker: – IRMB & ICGM, Montpellier, France

Technical Session VBioengineering (Focus Group - BE)Gene Delivery and Gene Editing (Focus Group - GDGE)

4:06 PM - 4:16 PM WEST

Biointeractive Gelatin Nanoparticles as a Nanoengineered Therapeutic Platform for Tissue Regeneration

Room: Auditorium I

Oral Abstract Speaker: – Chonnam National University

Technical Session VBioengineering (Focus Group - BE)Nanomedicine and Nanoscale Delivery (Focus Group - NND)

4:16 PM - 4:26 PM WEST

Dual Crosslinked Self Healing Hydrogel with Hemostatic, Antibacterial and Photothermal Functions for Wound Repair

Room: Auditorium I

Oral Abstract Speaker: – The University Medical Center Groningen

Technical Session VBioengineering (Focus Group - BE)

3:00 PM - 4:30 PM WEST

MDPI Editorial Board Meeting

Room: Room 105

Committee Meeting

4:30 PM - 5:00 PM WEST

Afternoon Coffee Break | Exhibit Hall & Posters

Room: Pavilion 2

Coffee BreakExhibit HallPoster HoursBreakNetworking

5:00 PM - 6:00 PM WEST

Beyond Boundaries: CRS Giants

Room: Auditorium I

Distinguished Speaker: – The University of Texas at Austin

General Session

6:00 PM - 8:00 PM WEST

Exhibit Hall & Posters

ReceptionFood & Beverage ProvidedExhibit HallPoster HoursNetworking

8:00 PM - 10:00 PM WEST

Closing Party | Exhibit Hall

ReceptionFood & Beverage ProvidedExhibit HallPoster HoursNetworking